Consortium
The PAT4CGT consortium is composed of a multidisciplinary group of internationally recognized CGT experts and companies across 6 EU member states and Switzerland.
PAT4CGT
PAT4CGT brings together stakeholders across the CGT manufacturing value chain
Project Coordinator with innovation management expertise-key to the success of this complex project
2 technology partners + 1 academic partner + 2 end-users of the technology
A highly interdisciplinary group with complementary expertise in industrial automation, Sensor technologies, CGT manufacturing process development
Internationally recognized experts across 6 EU countries plus Switzerland
Da Vinci Labs
Da Vinci Labs SAS is a deeptech accelerator based in the Touraine region of France.
Inspired by Leonardo da Vinci, the organisation provides research and innovation support services to leading European innovators.
Da Vinci Labs will leverage its expertise to identify, evaluate and manage new IP that emerges from the PAT4CGT project.
They will also manage all administrative, financial, contractual and legal aspects of the project.
Xavier Aubry, Managing Director
Limula
Limula is a Life Science Tools company based in Lausanne, Switzerland.
The Limula team is developing a modular platform technology for end-to-end CGT manufacturing, based on a novel bioreactor design. Its closed and automated cell processing system has great scalability potential, supporting process development towards commercialisation of highly personalised cancer treatments.
To achieve its ambition, Limula is working with cell therapy experts at the University of Geneva and other European clinical research centres, as well as biotechnology companies.
Limula brings a deep expertise in cell processing to the PAT4CGT consortium. The company will develop key components of the sensor cassette and integrate it to their bioreactor. Limula will also develop a risk assessment dossier, establishing a quality management system and creating a full regulatory dossier and roadmap for the proposed PAT platform.
Contact Details
Dr. Luc Henry, Chief Executive Officer
TU Wien is among the most successful technical universities in Europe
It is also Austria’s largest scientific-technical research and educational institution.
Assoc. Prof. Oliver Spadiut, Head of Research Area Biochemical Engineering, leads the Bioprocess Technology Research Group at TU Wien. The research group focuses on sound science and transferable methods for efficient bioprocess development.
As part of the PAT4CGT project, the TU Wien team will develop a methodology and the algorithms necessary to convert data output from the sensor platform into process knowledge using advanced data analytics.
Contact Details
Assoc. Prof. Oliver Spadiut, Head of Research Area Biochemical Engineering
Technische Universität Wien
Jobst Technologies GmbH
Jobst Technologies GmbH is the global performance leader for biosensor monitoring applications.
The company is developing multi-biosensing devices in vivo biosensors, sensors for clinical analyzers, and sensing- and control-microsystems for biotechnology monitoring.
Researchers at Jobst Technologies GmbH will lean on these capabilities to develop the PAT4CGT platform hardware components up to a stage where they can be evaluated in use cases, under laboratory conditions.
They will also adapt their sensor technologies to meet criteria for CGT manufacturing processes and integrate them into the first PAT4CGT prototype.
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Gerhard Jobst, Managing Director
Exothera
Exothera delivers customised process development and GMP manufacturing services for viral vector projects.
The Belgian based company supports the generation of cell and gene products, viral vaccine or oncolytic virus therapy development from pre-clinical to cGMP manufacturing.
Exothera will help test the PAT4CGT prototype by monitoring critical process parameters of established standard operating procedures.
The company will also deliver data on the production of viral vectors and compare results obtained using in-line and at-line sensors technologies.
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Jonathan Lecocq
Stemmatters
Stemmatters is a contract development and manufacturing organization
The company specialises in the manufacturing of regenerative medicine products such as cell therapies and cell-derived biologicals.
As such, Stemmatters will play a leading role in the tech transfer process.
They will also install the platform prototype and train operators before evaluating and benchmarking the performance of the second-generation platform prototype in at least one feasibility run.
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Dr. Pedro M. Costa, Head of Operations
Crowdhelix
Crowdhelix is an Open Innovation platform that forges links between an international network of excellent researchers and innovative companies.
Through the application of AI technology, Crowdhelix connects businesses, universities, and research centres to develop their ideas into funding proposals and deliver cutting-edge projects.
Crowdhelix will lead PAT4CGT’s communication and dissemination activities.
They will also create a virtual cluster/ community, the CGT Helix, on the Crowdhelix platform, which will act as the source of dissemination and exploitation during and after the project.
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